A group of scientists at the Salk Institute for Biological Studies may have just stumbled upon an antidote that reverses the natural ageing process in man.
In an experiment, Salk scientists were able to rejuvenate mice with premature aging disease progeria by engaging in a spot of cellular reprogramming.
This involved converting cells into what are referred to as induced pluripotent stem cells, capable of indefinitely dividing and transforming into any cell type present in the body.
When the reprogrammed cells were examined, it was found that they exhibited a reversal of multiple hallmarks associated with aging. Unlike other studies which have used similar techniques, in this case, the reverse-aging cells maintained their skin-cell identities.
As a result of the work, the scientists report that the mice looked younger and had improved cardiovascular and other organ function. The researchers suggest that the discovery could also be used to help humans.
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