Novak Djokovic has been knocked out of the Monte Carlo Masters by world number 55 Jiri Vesely.
The world number one was beaten 6-4 2-6 6-4 by the Czech, his first exit as early as the second round since the Madrid Masters in 2013.
Vesely, 22, had never before beaten a player ranked in the world’s top 10.
Read also: Injured Ferrer withdraws from Monte Carlo
Eleven-time Grand Slam winner Djokovic had won his past 22 matches in Masters competitions and nine of his past 10 tournaments.
Meanwhile, Aljaz Bedene found Rafael Nadal too hot to handle on the clay in Monaco.
It was a creditable performance from the British No 2 in the second round of the Monte-Carlo Masters, but he held serve only four times in a 6-3, 6-3 defeat.
Nadal has been dethroned, having won the tournament eight times in a row between 2005 and 2012, with Novak Djokovic winning twice and Stan Wawrinka once over the past three years.
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